Anti-inflammatory drug found to help adults with severe schizophrenia

January 23, 2024
Mental Health Neuroscience Research Australia (NeuRA)

  • Schizophrenia affects 35 million adults worldwide each year
  • First study to find that monoclonal antibody drug can provide symptom relief to people with schizophrenia and inflammation
  • Randomised control trial
  • Opens pathways towards personalised treatment of schizophrenia

Research conducted at Neuroscience Research Australia has found that an injection of an anti-flammatory biological known as Canakinumab in patients with schizophrenia and elevated inflammation brought about a decrease in psychotic symptom severity and inflammation. The research was published in Brain, Behavior, and Immunity.

Our study is the first clinical trial of anti-inflammatories for people with schizophrenia who also have an elevated inflammation status,” says Professor Cyndi Shannon Weickert, lead author on the study and Senior Professor at Neuroscience Research Australia.

Read more: Anti-inflammatory drug found to help adults with severe schizophrenia